Pharmacodynamics
An enzyme preparation that improves digestion processes. Pancreatic enzymes that make up the drug facilitate the breakdown of proteins, fats, carbohydrates, which leads to their complete absorption in the small intestine.
Creon® 10000 contains pork pancreatin in the form of enteric-coated (acid-resistant) coated mini-microspheres in gelatin capsules. The capsules dissolve quickly in the stomach, releasing hundreds of minimicrospheres. This principle is designed to thoroughly mix the minimicrospheres with the intestinal contents, and ultimately to better distribute the enzymes once released within the intestinal contents. When the minimicrospheres reach the small intestine, the enteric membrane is rapidly destroyed (at pH> 5.5), enzymes with lipolytic, amylolytic and proteolytic activity are released, which leads to the breakdown of fats, carbohydrates and proteins. The digested substances are then either absorbed directly or further hydrolyzed by intestinal enzymes.