"Pantethine is a particular form of pantothenic acid, which is more commonly known as Vitamin B5. Like the more familiar Vitamin B5 form, Pantethine is also useful for wound healing, immune system support, improving the metabolism of fats, and reducing stress levels. Both Pantethine and pantothenic acid help maintain normal growth and functioning of the nervous system. Both compounds convert choline into acetylcholine, which is crucial to optimal brain functioning. They are also noted for their role in supporting adrenal gland sufficiency.
Pantethine, which is the biologically active form of pantothenic acid, has the added benefit of reducing serum cholesterol levels and increasing HDL (the so-called good cholesterol). As a precursor to co-enzyme A (CoA), Pantethine is responsible for facilitating the release of energy from fats and carbohydrates, and has become a popular supplement over the last decade due to its ability to boost energy levels and increase immune response.
Pantethine plays a valuable role in decreasing the negative effects of the typical Western lifestyle. Detrimental compounds known as acetaldehydes can progressively accumulate in body tissues from the effects of pollution, vehicle emissions, cigarettes and illegal drugs, as well as moderate to excessive alcohol intake. Chronic exposure to these chemicals results in an overall lowering of vitality due to both incomplete metabolism of energy-rich foods, and the impairment of the oxygen-carrying potential of red blood cells.
Symptoms of Pantethine deficiency are numerous and relate principally to malfunctioning of the nervous system and a decrease in stamina and energy. These include nervousness, rapid heart rate, restlessness, fatigue, depression, adrenal insufficiency, weakness, hypoglycemia, low blood pressure, and a range of gastrointestinal disorders.
Supplementation with Pantethine assists with decreasing overall cholesterol levels, accompanied by an increase in the HDL/LDL ratio, which is beneficial to good cardiovascular health. Pantethine can also reduce the stickiness of blood platelets, thus lowering the incidence of heart attack and stroke. It offers protection against the damaging effects of aldehydes due to environmental pathogens such as cigarette smoke, exhaust fumes, and alcohol, particularly on chemically-sensitive persons.
Pantethine is a water-soluble member of the Vitamin B group and as such requires regular daily intake from food and supplementation. Excess amounts are excreted in the urine. There are no known side effects or symptoms of toxicity."